WebMay 21, 2013 · A Pooled Analysis of the HGS1006-C1056 (BLISS-52) and HGS1006-C1057 (BLISS-76) Studies The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. WebJan 24, 2024 · Significant reductions in severe flare were observed with belimumab 10 mg/kg IV over 52 weeks in the BLISS-52 study 18 and with belimumab 1 mg/kg IV over 76 weeks in the BLISS-76 study 17. Onset …
Impact of belimumab on patient-reported outcomes in systemic lupus ...
WebAug 30, 2011 · BLISS-76, the second phase III clinical trial of belimumab in SLE, was conducted primarily in North America and Europe. Treatment continued through week … Arthritis & Rheumatology, an official journal of the American College of … WebThe BLISS-52 trial involved 865 patients from Latin America, the Asia–Pacific region, and eastern Europe. The BLISS-76 trial involved 819 patients from North America, Central … ticketmaster fort worth rodeo
Two-Year, Randomized, Controlled Trial of Belimumab in …
WebPost hoc analysis of the BLISS-76 population at study baseline. We performed a post hoc analysis of the BLISS-76 trial, assessing data from the baseline study visit, where patients were expected to have a high level of disease activity. We analysed the performance of the SLE-DAS cut-off value for moderate/severe disease activity (prospectively ... WebAug 29, 2024 · Strand V, Levy RA, Cervera R, Petri MA, Birch H, Freimuth WW, Zhong ZJ, Clarke AE, BLISS-52 and -76 Study Groups. Improvements in health-related quality of life with Belimumab, a B-lymphocyte stimulator-specific inhibitor, in patients with autoantibody-positive systemic lupus erythematosus from the randomised controlled BLISS trials. WebMethods This post hoc integrated analysis (GSK Study 116559) included safety data from six randomised, placebo-controlled belimumab trials (BLISS-76, BLISS-52, BLISS-SC, North East Asia study, LBSL02, EMBRACE; n=4170). The BASE study provided additional safety data (n=4003). Efficacy data were from five of the trials. Older adults (≥65 years) … the lion king laserdisc 1995