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Human hsd17b13

WebHsd17b13 Name hydroxysteroid (17-beta) dehydrogenase 13 Synonyms Pan1b Feature Type protein coding gene IDs MGI:2140804 NCBI Gene: 243168 Alliance gene page Transcription Start Sites 5 TSS Location & Maps more Sequence Map Chr5:104103308-104125254 bp, - strand From NCBI annotation of GRCm39 Genetic Map Chromosome 5, … Web17β-Hydroxysteroid dehydrogenase type 13 also known as 17β-HSD type 13 is an enzyme that in humans is encoded by the HSD17B13 gene. [5] [6] 17β-HSD13 is significantly up-regulated in the liver of patients with non-alcoholic fatty liver disease (NAFLD) and enhances lipogenesis. [7] References [ edit]

Hsd17b13 Deficiency Does not Protect Mice From

WebMutant HSD17B13 variants devoid of enzymatic function have been demonstrated to be protective from cirrhosis and liver cancer, supporting the development of HSD17B13 as a … WebHSD17B13 (Hydroxysteroid 17 Beta Dehydrogenase 13) is a Protein Coding gene. Diseases associated with HSD17B13 include5 Alpha Reductase … dallas dmc https://beni-plugs.com

A Protein-Truncating HSD17B13 Variant and Protection …

WebHSD17B13 Reactivity: Human Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13) ELISA Kit HSD17B13 Reactivity: Cow Colorimetric Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate WebDescription: Homo sapiens hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13), transcript variant A, mRNA. (from RefSeq NM_178135) Gencode Transcript: ENST00000328546.5 Gencode Gene: ENSG00000170509.12 Transcript (Including UTRs) Web17-b hydroxysteroid dehydrogenase 13 (HSD17B13) belongs to a 15-member family that is involved in various metabolic processes, including steroid hormones, fatty ac-ids, cholesterol, and bile acids (1). The human HSD17B13 gene is located on chromosome 4 (4q22.1), and its expres-sion is highly restricted to the liver, specifically in hepato- dallas divorce attorney reviews

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Human hsd17b13

HSD17B13 Antibody (NBP3-04837): Novus Biologicals

WebMar 30, 2024 · Recombinant human HSD17B13 protein was purified from Escherichia coli transformed with plasmid DNA harboring HSD17B13 transcript A or transcript D. Enzymatic activity was determined through... WebJun 1, 2024 · Recent study showed that hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), an enzyme with unknown biological function, is a novel liver-specific lipid droplet (LD)-associated protein in mouse and humans. HSD17B13 expression is markedly upregulated in patients and mice with non-alcoholic fatty liver disease (NAFLD).

Human hsd17b13

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WebPROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. HSD17B13 INFORMATION. Proteini. Full gene name according to HGNC. Hydroxysteroid 17-beta … WebApr 13, 2024 · Here are some possible explanations for the discrepancy between human and mouse loss-of-function mutations: (1) Different pathways: Loss-of-function (LoF) for the mouse and human HSD17B13 gene effect different fundamental pathways, as the two species are just different; (2) Different genes: The knockout mouse effects another gene …

WebMar 29, 2024 · HSD17B13 rs72613567 protects against liver diseases and histological progression of nonalcoholic fatty liver disease: a systematic review and meta-analysis. … HSD17B13 - hydroxysteroid 17-beta dehydrogenase 13. Predicted to enable … WebJun 1, 2024 · HSD17B13 is a newly identified liver restricted LD-associated protein. • HSD17B13 expression is markedly upregulated in the livers of patients and mice with …

WebApr 3, 2024 · Published human genetic data indicate that a loss of function mutation in HSD17B13 provides strong protection against alcoholic hepatitis, cirrhosis, and NASH, with approximately 30-50% risk ... WebView more Antibodies that detect HSD17B13 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry and ELISA. These antibodies target HSD17B13 in Human, Rat and Mouse samples. Our HSD17B13 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit …

WebRecombinant Human HSD17B13 protein (Tagged) is a HEK 293 Full length protein 1 to 300 aa range, >=90% purity and validated in SDS-PAGE. Recombinant Human HSD17B13 … marijuana scale amazonWebBI-3231 (BI 3231) is a potent, selective HSD17B13 (hydroxysteroid 17β-dehydrogenase 13) inhibitor with enzyme IC50 of 1 and 14 nM for human and mouse HSD17B13, respectively. BI-3231 displays excellent selectivity versus the structurally related homolog HSD17B11 (IC50>10 uM), as well as good selectivity in a commercial SafetyScreen44 panel, Cerep. dallas d logoWebOnly some individuals with obesity develop liver fibrosis due to non-alcoholic fatty liver disease (NAFLD-fibrosis). We determined whether detailed assessment of lifestyle factors in addition to physical, biochemical and genetic factors helps in identification of these patients. A total of 100 patients with obesity (mean BMI 40.0 ± 0.6 kg/m2) referred for bariatric … dallas dline