Webtrough. / ( trɒf) /. noun. a narrow open container, esp one in which food or water for animals is put. a narrow channel, gutter, or gulley. a narrow depression either in the land surface, … WebTrough means just prior to the next dose of medication. For example if a medication is given every 12 hours and the patient's last dose was at 8pm, then the TDM sample needs to be …

Therapeutic Drug Monitoring - Testing.com

Web• An early trough (6-hours prior to dose) should be considered in patients demonstrating acute changes in renal function or suspicion of extended interval failure. Aiming for a level < 1 mcg/mL approximately 6-hours prior to the next dose ensures there is a drug-free window in order to minimize drug accumulation within the proximal tubules. WebTrough An early trough 6-hours before the 2nd dose (A paired peak/trough should be timed after the same dose. 7 mg/kg Q24H Dosing: Random Level approximately 8 – 10 hours … heather o\u0027rourke illness

When should trough levels of vancomycin be drawn?

WebTrough concentration: the concentration of drug in the blood immediately before the next dose is administered, although this does not necessarily represent the lowest … WebSynonyms of trough 1 a : a long shallow often V-shaped receptacle for the drinking water or feed of domestic animals b : any of various domestic or industrial containers 2 a : a … WebNov 9, 2024 · Therapeutic drug monitoring is the measurement of specific drugs and/or their breakdown products (metabolites) at timed intervals to maintain a relatively constant concentration of the medication in the blood. Some of the monitored drugs tend to have a narrow “therapeutic index,” which is a ratio between the toxic and therapeutic (effective ... movies and more store